SafeBeat Rx

Menu

Research

Funded Projects

 
NIH NHLBI 3R44HL167294    01/2025-06/2025                    
PD/PI(s): Rachita Navara, Kunj Patel, Edward Gerstenfeld
Administrative supplement award to support Postdoctoral Fellow Margaret Ferrari
A novel, AI-based ECG analysis and drug dosing recommendation technology to safely start antiarrhythmic medications to treat atrial fibrillation 
 
NIH NHLBI R43HL174305      09/2024-02/2025                    
PD/PI(s): Rachita Navara, Kunj Patel
A novel, smartwatch-enabled, automated mobile heart rhythm analysis technology to start antiarrhythmic medications safely at home                                                              
 
NIH NHLBI R44HL167294     07/2024-06/2026                    
A novel, AI-based ECG analysis and drug dosing recommendation technology to safely start antiarrhythmic medications to treat atrial fibrillation
PD/PI(s): Rachita Navara, Kunj Patel, Edward Gerstenfeld
 

Research Works 

  1. R Navara, M Bharath, A Sen, R Adhi, E Chua, R Desai, Y Wang, A Soi, N Le, N Naidu, J Rho, M Ferrari, W McHugh, K Patel (2025, April 24-27). Assessing the Educational Value of TikTok Content Related to Atrial Fibrillation. Heart Rhythm Society Annual Meeting, San Diego, CA, United States.

  2. R Navara, M Ferrari, N Naidu, J Higgins, W McHugh, M Bharath, K Patel (2025, April 24-27). QTc-Guided Software for Precise Titration of Antiarrhythmic Agents: Novel Approach to Safe Drug Initiation. Heart Rhythm Society Annual Meeting, San Diego, CA, United States.

  3. R Navara, K Patel, B Kheiri, W McHugh, M Ferrari, D Corsi, A Sen, A Sinha, G Pavez, Z Tseng, E Gerstenfeld. CLINICAL PERFORMANCE OF NOVEL MACHINE-LEARNING BASED ANTIARRHYTHMIC DOSING SOFTWARE: A PROSPECTIVE STUDY. JACC. 2025 Apr, 85 (12_Supplement) 149. https://doi.org/10.1016/S0735-1097(25)00634-5 

  4. R Navara, K Patel, B Kheiri, W McHugh, M Ferrari, D Corsi, A Sen, A Sinha, G Pavez, Z Tseng, E Gerstenfeld (2025, March 28-30). Clinical Performance of Novel Machine-Learning Based Antiarrhythmic Dosing Software: A Prospective Study. American College of Cardiology, Chicago, IL, United States.

  5. R Navara , M Ferrari, A Soi, M Bharath, D Corsi, A Rathore, W McHugh, K Patel. Abstracts from the 30th Annual Atrial Fibrillation Symposium: Acute and Long-term Remote Monitoring of Antiarrhythmic Drug Titration for Atrial Fibrillation: A Case Series. Journal of Cardiovascular Electrophysiology, 2025. https://doi.org/10.1111/jce.16619

  6. R Navara, M Bharath, A Sen, R Adhi, E Chua, R Desai, Y Wang, A Soi, N Le, M Ferrari, W McHugh, K Patel. Abstracts from the 30th Annual Atrial Fibrillation Symposium: Educational analysis of atrial fibrillation social media content. Journal of Cardiovascular Electrophysiology, 2025. https://doi.org/10.1111/jce.16619

  7. R Navara, M Ferrari, Y Wang, S Jayakumar, M Bharath, A Sen, A Soi, A Martinez, W McHugh, K Patel. Abstracts from the 30th Annual Atrial Fibrillation Symposium: A novel software platform for automated QTc measurements demonstrates consistent accuracy among cardiologists. Journal of Cardiovascular Electrophysiology, 2025. https://doi.org/10.1111/jce.16619

  8. R Navara, M Ferrari, A Soi, M Bharath, D Corsi, A Rathore, W McHugh, K Patel (2025, January 16-18). Acute and Long-term Remote Monitoring of Antiarrhythmic Drug Titration for Atrial Fibrillation: A Case Series. AF Symposium, Boston, MA, United States.

  9. R Navara, M Bharath, A Sen, R Adhi, E Chua, R Desai, Y Wang, A Soi, N Le, M Ferrari, W McHugh, K Patel (2025, January 16-18). Educational Analysis of Atrial Fibrillation Social Media Content. AF Symposium, Boston, MA, United States.

  10. R Navara, M Ferrari, Y Wang, S Jayakumar, M Bharath, A Sen, A Soi, A Martinez, W McHugh, K Patel (2025, January 16-18). A Novel Software Platform for Automated QTc Measurements Demonstrates Consistent Accuracy among Cardiologists. AF Symposium, Boston, MA, United States.

  11. R Navara, D Corsi, A Rathore, M Ashary, J Devgun, K Malcolm, C Cheung, M Dopierala, D Chen, Y Hsieh, L Samikanu, E Ozkan, A Pollad, O Bolaji, F Ouedraogo, F Markson, R Joel, K Patel. Abstract 4144669: Hospital-at-Home Digital Health Testing in Underserved versus the General Population, Circulation 2024 Vol. 150 Issue Suppl_1. doi: 10.1161/circ.150.suppl_1.4144669 

  12. R Navara, D Corsi, A Rathore, M Ashary, J Devgun, K Malcolm, C Cheung, M Dopierala, D Chen, Y Hsieh, L Samikanu, E Ozkan, A Pollad, O Bolaji, F Ouedraogo, F Markson, R Joel, K Patel (2024, November 16-18). Hospital-at-Home Digital Health Testing in Underserved versus the General Population. American Heart Association Scientific Sessions, Chicago, IL, United States.

  13. D Corsi, R Navara, B Kheiri, K Patel, A Sinha, W McHugh, A Sen, K Kheiri, M Cho, I Montgomery, G Pavez, T Dewland, H Hsia, B Lee, J Olgin, Z Tseng, V Vedantham, R Lee, J Moss, G Marcus, E Gerstenfeld (2024, November 7-9). A Novel Machine Learning Algorithm for Safe Initiation of Antiarrhythmic Drugs. American Medical Association Research Challenge Semifinals, Virtual. 

  14. R Navara, D Chen, A Pallod, M Bharath, A Soi, B Paudel, K Patel (2024, October 17). Risk Factors for Adverse Events During Outpatient Antiarrhythmic Drug Initiation: Implications for Establishing Protocols. Hospital at Home Users Group Annual Meeting, Virtual.

  15. R Navara, D Chen, A Pallod, S Rai, A Nepal, M Ferrari, K Patel (2024, October 17). Patient Utilization of Remote Health Monitoring Technology at an Inner-City Clinic. Hospital at Home Users Group Annual Meeting, Virtual.

  16. R Navara, D Corsi, B Paudel, Y Wang, K Patel (2024, October 17). Feasibility of Outpatient Antiarrhythmic Drug Initiation in Patients with Atrial Fibrillation. Hospital at Home Users Group Annual Meeting, Virtual.

  17. R Navara, A Rathore, W McHugh, M Ferrari, A Sinha, M Bharath, D Chen, T Paul, A Pallod, K Patel. ID: 4122034 Successful Software-Guided Antiarrhythmic Drug Initiation and Extended QTc Monitoring: A Case Series on Atrial Fibrillation Treatment, Heart Rhythm 2024, 21(9): S787-S788, DOI: 10.1016/j.hrthm.2024.07.066

  18. K Patel, W McHugh, B Paudel, A Sinha, R deLeon, D Asfaha, K Raj, J Higgins, R Talupula, A Pallod, A Rathore, S Okoroanyanwu, R Navara. ID: 4122069 Machine Learning Algorithm for QTc Measurement and AAD Dosing Recommendations in Long QT mECG Dataset, Heart Rhythm 2024, 21(9): S786. DOI: 10.1016/j.hrthm.2024.07.064

  19. R Navara, B Paudel, A Rathore, A Pallod, S Sheth, E Ananth, M Cho, G Pavez, I Montgomery, R Ravuri, A Alvarez, R DeLeon, D Chen, M Dopierala, R Venkateswaran, J Higgins, W McHugh, K Patel. ID: 4122070 Performance of Novel Machine Learning Software: Automating QTc Measurement and AAD Dosing in a Prospective Cohort. Heart Rhythm 2024, 21(9):S786. DOI: 10.1016/j.hrthm.2024.07.063

  20. D Corsi, R Navara, A Pallod, K Patel. 4122071 Pioneering Antiarrhythmic Drug Initiation: A Patient’s Journey with Software-Guided Dosing, Heart Rhythm 2024, 21(9): S798-S799. DOI: 10.1016/j.hrthm.2024.07.088

  21. R Navara, A Rathore, W McHugh, M Ferrari, A Sinha, M Bharath, D Chen, T Paul, A Pallod, K Patel (2024, September 5-7). Successful Software-Guided Antiarrhythmic Drug Initiation and Extended QTc Monitoring: A Case Series on Atrial Fibrillation Treatment.  Heart Rhythm Innovation (HRX), Atlanta, GA, United States

  22. K Patel, W McHugh, B Paudel, A Sinha, R deLeon, D Asfaha, K Raj, J Higgins, R Talupula, A Pallod, A Rathore, S Okoroanyanwu, R Navara (2024, September 5-7). Machine Learning Algorithm for QTc Measurement and AAD Dosing Recommendations in Long QT mECG Dataset. Heart Rhythm Innovation (HRX), Atlanta, GA, United States.

  23. R Navara, B Paudel, A Rathore, A Pallod, S Sheth, E Ananth, M Cho, G Pavez, I Montgomery, R Ravuri, A Alvarez, R DeLeon, D Chen, M Dopierala, R Venkateswaran, J Higgins, W McHugh, K Patel (2024, September 5-7). Performance of Novel Machine Learning Software: Automating QTc Measurement and AAD Dosing in a Prospective Cohort. Heart Rhythm Innovation (HRX), Atlanta, GA, United States.

  24. D Corsi, R Navara, A Pallod, K Patel (2024, September 5-7). Pioneering Antiarrhythmic Drug Initiation: A Patient’s Journey with Software-Guided Dosing. Heart Rhythm Innovation (HRX), Atlanta, GA, United States.

  25. K Patel, B Paudel, W McHugh, A Sinha, D Asfaha, S Okoroanyanwu, K Raj, O Bolaji, R Talupula, R deLeon, J Higgins, R Navara. PO-01-051: NOVEL MACHINE LEARNING ALGORITHM FOR QTC MEASUREMENT AND ANTIARRHYTHMIC DOSING RECOMMENDATIONS IN A DE_IDENTIFIED 12L ECG DATASET. Heart Rhythm. 2024; 21(5S): S190. doi: 10.1016/j.hrthm.2024.03.642

  26. K Patel, B Paudel, W McHugh, A Sinha, D Asfaha, S Okoroanyanwu, K Raj, O Bolaji, R Talupula, R deLeon, J Higgins, R Navara (2024, May 16-18). Novel Machine Learning Algorithm for Qtc Measurement and Antiarrhythmic Dosing Recommendations in a De-identified 12L ECG Dataset. Heart Rhythm Society Annual Meeting, Boston, MA, United States.

  27. R Navara, W Mchugh, A Pallod, K Raj, A Sinha, M Deshpande, Y Wang, S De, R deLeon, O Bolaji, D Asfaha, S Okoroanyanwu, B Paudel, R Manohar, K Patel. Usability of novel beat-by-beat ECG annotation software portal for generating large-scale machine learning training datasets. Europace. 2024 May 24;26(Suppl 1):euae102.580. doi: 10.1093/europace/euae102.580

  28. R Navara, W Mchugh, A Pallod, K Raj, A Sinha, M Deshpande, Y Wang, S De, R deLeon, O Bolaji, D Asfaha, S Okoroanyanwu, B Paudel, R Manohar, K Patel (2024, April 7-9). Usability of novel beat-by-beat ECG annotation software portal for generating large-scale machine learning training datasets. European Society of Cardiology, Berlin, Germany.

  29. R Navara, B Paudel, M Adhaduk, J Devgun, C Cheung, M Dopierala, D Chen, Y Hsieh, L Samikanu, E Ozkan, O Bolaji, F Ouedraogo, F Markson, D Asfaha, B Kheiri, S Sheth, E Ananth, R Ravuri, K Patel. PREDICTIVE FACTORS FOR ADVERSE OUTCOMES IN ATRIAL FIBRILLATION PATIENTS WITH SOTALOL AND DOFETILIDE INITIATION. JACC. 2024 Apr, 83 (13_Supplement) 226. doi: 10.1016/S0735-1097(24)02216-2

  30. R Navara, D Chen, M Lee, J Devgun, Y Hsieh, C Cheung, O Bolaji, F Ouedraogo, F Markson, E Ozkan, L Samikanu, D Asfaha, B Kheiri, B Paudel, M Dopierala, M Gupta, R Ravuri, E Ananth, S Sheth, K Patel. ATRIAL FIBRILLATION PATIENT PERSPECTIVE SURVEY ON ALTERNATIVE SETTINGS FOR ANTIARRHYTHMIC DRUG INITIATION. JACC. 2024 Apr, 83 (13_Supplement) 148. DOI: 10.1016/S0735-1097(24)02138-7

  31. R Navara, B Paudel, M Adhaduk, J Devgun, C Cheung, M Dopierala, D Chen, Y Hsieh, L Samikanu, E Ozkan, O Bolaji, F Ouedraogo, F Markson, D Asfaha, B Kheiri, S Sheth, E Ananth, R Ravuri, K Patel (2024, April 6-8). Predictive Factors for Adverse Outcomes in Atrial Fibrillation Patients with Sotalol and Dofetilide Initiation. American College of Cardiology, Atlanta, GA, United States.

  32. R Navara, D Chen, M Lee, J Devgun, Y Hsieh, C Cheung, O Bolaji, F Ouedraogo, F Markson, E Ozkan, L Samikanu, D Asfaha, B Kheiri, B Paudel, M Dopierala, M Gupta, R Ravuri, E Ananth, S Sheth, K Patel (2024, April 6-8). Atrial Fibrillation Patient Perspective Survey on Alternative Settings for Antiarrhythmic Drug Initiation. American College of Cardiology, Atlanta, GA, United States.

  33. R Navara, B Paudel, E Ananth, S Sujay, J Devgun, D Lucy, D Chen, A Pallod, M Dopierala, R Ravuri, E Ozkan, B Kheiri, K Malcolm, R Venkateswaran, A Alvarez Martinez, R DeLeon, J Higgins, K Patel.  Abstract 18508: Usability of Novel Automated Software for Guiding Remote Titration of Antiarrhythmic Drugs. Circulation 2023 Vol. 148 Issue Suppl_1 Page A18508. DOI: 10.1161/circ.148.suppl_1.18508. 

  34. R Navara, R Ravuri, J Devgun, R Kumar, E Ozkan, B Paudel, D Lucy, E Ananth, S Sujay, M Dopierala, D Chen, A Pallod, B Kheiri, K Malcolm, R Venkateswaran, A Martinez, R DeLeon, J Higgins, K Patel. Abstract 18336: Accuracy of Antiarrhythmic Drug Dosing Using a Computer-Guided Decision Tree Model. Circulation 2023 Vol. 148 Issue Suppl_1 Pages A18336-A18336. doi:10.1161/circ.148.suppl_1.18336

  35. R Navara, B Paudel, E Ananth, S Sujay, J Devgun, D Lucy, D Chen, A Pallod, M Dopierala, R Ravuri, E Ozkan, B Kheiri, K Malcolm, R Venkateswaran, A Alvarez Martinez, R DeLeon, J Higgins, K Patel (2023, November 11-13). Usability of Novel Automated Software for Guiding Remote Titration of Antiarrhythmic Drugs. American Heart Association Scientific Sessions, Philadelphia, PA, United States.

  36. R Navara, R Ravuri, J Devgun, R Kumar, E Ozkan, B Paudel, D Lucy, E Ananth, S Sujay, M Dopierala, D Chen, A Pallod, B Kheiri, K Malcolm, R Venkateswaran, A Martinez, R DeLeon, J Higgins, K Patel (2023, November 11-13). Accuracy of Antiarrhythmic Drug Dosing Using a Computer-Guided Decision Tree Model. American Heart Association Scientific Sessions, Philadelphia, PA, United States.

  37. R Navara, J Devgun, C Cheung, R Venkateswaran, E Ozkan, M Ashary, S Goh, M Dopierala, O Bolaji, K Malcom, R Joel, J Uzodinma, A  Alvarez, B Sackett, R deLeon, J Higgins, D Lucy, K. Patel. PO-04-209 A NOVEL MACHINE LEARNING (ML) ALGORITHM TO MEASURE THE CORRECTED QT INTERVAL FROM MOBILE ECGS WITH HIGH ACCURACY AND PRECISION. Heart Rhythm 2023; 20(5): S617. DOI: 10.1016/j.hrthm.2023.03.1300

  38. R Venkateswaran, R Navara, K Malcolm, K Patel, M Scheinman. PO-04-103 WIDE COMPLEX TACHYCARDIA IN ACUTE ANTI-NMDA RECEPTOR ENCEPHALITIS. Heart Rhythm 2023; 20(5): S594-S595. DOI: 10.1016/j.hrthm.2023.03.1258

  39. R Navara, O Bolaji, F Ouedraogo, F Markson, K Patel. PO-01-234 DETECTING RISK OF HIGH HEALTH CARE UTILIZATION IN PATIENTS WITH ATRIAL FIBRILLATION: A SUPERVISED MACHINE LEARNING APPROACH. Heart Rhythm 2023, 20(5): S198-S199. DOI: 10.1016/j.hrthm.2023.03.597

  40. R Navara, J Devgun, C Cheung, R Venkateswaran, E Ozkan, M Ashary, S Goh, M Dopierala, O Bolaji, K Malcom, R Joel, J Uzodinma, A  Alvarez, B Sackett, R deLeon, J Higgins, D Lucy, K. Patel (2023, May 17- 20). A Novel Machine Learning (ML) Algorithm to Measure the Corrected QT Interval From Mobile ECGs with High Accuracy and Precision. Heart Rhythm Society Annual Meeting, New Orleans, LA, United States.

  41. R Venkateswaran, R Navara, K Malcolm, K Patel, M Scheinman (2023, May 17- 20). Complex Tachycardia in Acute Anti-Nmda Receptor Encephalitis. Heart Rhythm Society Annual Meeting, New Orleans, LA, United States.

  42. R Navara, O Bolaji, F Ouedraogo, F Markson, K Patel (2023, May 17- 20). Detecting Risk of High Health Care Utilization in Patients With Atrial Fibrillation: A Supervised Machine Learning Approach. Heart Rhythm Society Annual Meeting, New Orleans, LA, United States.